The author examines the nature of Herzen's relationship with Slavophilism in its conflict with Westernism and discusses his incipient religiosity.

The publication of the Critique of Pure Reason by Immanuel Kant marked the beginning of an intellectual revolution not only in Philosophy, but also in other spheres of intellectual activity. Every year interest to this work is only growing up, especially in the context of the development of cognitive sciences and technologies related to the development and implementation of artificial intelligence systems. However, both Kant’s contemporaries and subsequent generations of researchers had questions about the basic concepts, outlined in the first (...) Critique. Nikolay Lossky became one of such outstanding experts in Kant’s philosophy, who carried out a metacritique of transcendental idealism. His analysis is interesting because it is characterized by consistency, depth and inclusiveness, despite the fact that he was not a supporter of Kant’s philosophy. The proposed article explicates the main points of the metacritique of pure reason carried out by Lossky. The aim is to systematize the advantages and disadvantages of transcendental idealism highlighted by him in order to assess the validity of objections and identify points that paradoxically escaped Lossky’s attention. In particular, it is shown that the highest evaluation of Lossky is awarded to Kant’s efforts to create an epistemology that does not rely as presuppositions on any other branches of human knowledge; the resolution of contradictions between Empiricism and Rationalism; the creation of the doctrine of synthetic rationality and transcendental logic; the idea of the need for the immanence of knowledge to consciousness. Lossky identified as the key shortcomings of transcendental idealism a range of contradictions grouped around such concepts as the things in themselves, affection, experience, inner sense, transcendental schema, and unity of apperception. At the same time, it is shown that such a key concept for Kant’s theoretical philosophy as transcendental reflection has disappeared from the Lossky’s field of consideration. The study is preceded by a brief description of Lossky’s characteristics, including personal ones, as a meta-critic of pure reason. (shrink)

The article compares views of C.G. Jung and N.O. Lossky on the nature of time, including in the context of contemporary to them physical theories - quantum mechanics by W. Pauli and relativistic physics by A. Einstein. In particular, the author points to the similarity of ideas of both thinkers that the psyche relativizes time not only subjectively, but also objectively. Jung and Lossky provide this statement with a similar empirical basis, for example, the researches of T. Flournoy, as well (...) as similar theoretical arguments by postulating a fundamental acausal principle of the connection of all things, which is better suited for describing psychic and some physical phenomena than the classical causal explanation. In analytical psychology, such a principle is synchronicity, in hierarchical personalism - gnoseological coordination. Both concepts are genetically related to the G.W. Leibniz idea of pre-established harmony, which was reinterpreted by Jung and Lossky through different worldview foundations. Jung in his reasoning relied on the transcendental idealism of I. Kant, the principle of complementarity and the discoveries of quantum mechanics, Lossky - on intuitivism, the principle of subordination and on his own interpretation of Einsteins theories. Jung comes to the conclusion that the psyche has a timeless character, and Lossky comes to the conclusion that it has a super-temporal character. Jungs timelessness indicates the transcendental nature of psyche and the strive to get away from the classical causal explanation, saving it according to the principle of complementarity only to consider the phenomenal side of being and mainly physical processes. One of the pioneers of quantum mechanics Pauli was of the same opinion in general. Because of there is nothing transcendent in hierarchical personalism, Losskys super-temporality is of a strive to find a deeper basis for occurring in time processes, and, according to the principle of subordination, to include time in the hierarchical structure of the universe, prescribing for it a role of one of the two key forms of psychic and psycho-material processes characteristic of a certain stage of being. (shrink)

Extracellular nucleic acids are found in different biological fluids in the organism and in the environment: DNA is a ubiquitous component of the organic matter pool in the soil and in all marine and freshwater habitats. Data from recent studies strongly suggest that extracellular DNA and RNA play important biological roles in microbial communities and in higher organisms. DNA is an important component of bacterial biofilms and is involved in horizontal gene transfer. In recent years, the circulating extracellular nucleic acids (...) were shown to be associated with some diseases. Attempts are being made to develop noninvasive methods of early tumor diagnostics based on analysis of circulating DNA and RNA. Recent observations demonstrated the possibility of nucleic acids exchange between eukaryotic cells and extracellular space suggesting their participation in so far unidentified biological processes. BioEssays 29:654–667, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

We discuss N. I. Vavilov’s 1922 landmark publication, “The Law of Homologous Series in Variation,” and highlight its salient points. Vavilov drew upon his considerable experience in the field with wild and cultivated crop plants and summarized what he noticed in the form of a law. The law stated that comparable variant forms tended to appear in different varieties of the same species, different species of the same genus, different genera of the same family, and so on. His survey of (...) the older literature suggested that the law applied to multicellular animals as well. Vavilov acknowledged that such “parallel” series might be the outcome of convergent evolution (as conventionally understood). At the same time, by way of an alternative hypothesis, he posed a question that continues to engage evolutionary biology to this day. Namely, does the existence of such parallelisms reflect underlying structural and developmental principles (based on the laws of physics and chemistry) which constrain the range of possible plant and animal forms? Vavilov’s original 1922 paper from the _Journal of Genetics_ (12:47–89) is available as supplementary material in the online version of this article. (shrink)

The morbidity of tick‐borne encephalitis (TBE) varies yearly by as much as 10‐fold among the people of Western Siberia. This long‐term variation is dependent on many factors such as the density of the tick populations, the prevalence of TBE virus (TBEV) among sub‐adult ticks, the yearly virulence of the TBEV, and prophylactic measures. Here we highlight the role of small mammal hosts in the circulation of TBEV through the ecosystem. Refining classical models of non‐viremic horizontal transmission, we emphasize the recently (...) understood fact that the physiological and immunological status of the small mammal hosts affects the tick and virus‐host interactions. In addition to its theoretical interest, our approach may lead to some practical improvements in the precision of epidemiological forecasts and perhaps in forestalling the severity of outbreaks of TBE, or, at least, in forewarning medical authorities and the general public of impending TBE outbreaks. (shrink)

At some point, a limit must be set on the extensive development of the explanatory principle beyond which its further constructive use is possible only though its intensive elaboration.

Анализируется круг проблем, к которым было приковано преимущественное внимание русских философов указанного периода. Это - идущее от А. С. Хомякова философское осмысление Божественного Триединства.

Stable evolutionary strategy of Homo sapiens (SESH) is built in accordance with the modular and hierarchical principle and consists of the same type of self-replicating elements, i.e. is a system of systems. On the top level of the organization of SESH is the superposition of genetic, social, cultural and techno-rationalistic complexes. The components of this triad differ in the mechanism of cycles of generation - replication - transmission - fixing/elimination of adoptively relevant information. This mechanism is implemented either in accordance (...) with the Darwin-Weismann modus, or according to the Lamarck modus, the difference between them is clear from the title. The integral attribute of the system of systems including ESSH is the production of evolutionary risks. The sources of evolutionary risk for stable adaptive strategy of Homo sapiens are the imbalance of (1) the intra-genomic co-evolution (intragenomic conflicts); (2) the gene-cultural coevolution; (3) the inter-cultural co-evolution; (4) techno-humanitarian balance; (5) intertechnological conflicts (technological traps). At least phenomenologically the components of the evolutionary risk are reversible, but in the aggregate they are in potentio irreversible destructive ones for bio-social, and cultural self-identity of Homo sapiens. When the actual evolution is the subject of a rationalist control and/or manipulation, the magnitude of the 4th and 5th components of the evolutionary risk reaches the level of existential significance. (shrink)

The theory of evolution of complex and comprising of human systems and algorithm for its constructing are the synthesis of evolutionary epistemology, philosophical anthropology and concrete scientific empirical basis in modern (transdisciplinary) science. «Trans-disciplinary» in the context is interpreted as a completely new epistemological situation, which is fraught with the initiation of a civilizational crisis. Philosophy and ideology of technogenic civilization is based on the possibility of unambiguous demarcation of public value and descriptive scientific discourses (1), and the object and (...) subject of the cognitive process (2). Both of these attributes are no longer valid. For mass, everyday consciousness and institutional philosophical tradition it is intuitively obvious that having the ability to control the evolutionary process, Homo sapiens came close to the borders of their own biological and cultural identity. The spontaneous coevolutionary process of interaction between the «subject» (rational living organisms) and the «object» (material world), is the teleological trend of the movement towards the complete rationalization of the World as It Is, its merger with the World of Due. The stratification of the global evolutionary process into selective and semantic (teleological) coevolutionary and therefore ontologically inseparable components follows. With the entry of anthropogenic civilization into the stage of the information society, firsty, the post-academic phase of the historical evolution of scientific rationality began, the attributes of which are the specific methodology of scientific knowledge, scientific ethos and ontology. Bioethics as a phenomenon of intellectual culture represents a natural philosophical core of modern post- academic (human-dimensional) science, in which the ethical neutrality of scientific theory principle is inapplicable, and elements of public-axiological and scientific-descriptive discourses are integrated into a single logic construction. As result, hermeneutics precedes epistemology not only methodologically, but also meaningfully, and natural philosophy is regaining the status of the backbone of the theory of evolution – in an explicit form. (shrink)

The phenomenon of rationalism and irrationalism, contextually related to the transformation methodology and the social function of modern (post-industrial) science – social verification, interpretation and knowledge, etc., are analyzes.

This is a review of the book: Sheehan H. Marxism and the Philosophy of Science. A Critical History. The First Hundred Years. (L.: Verso, 2017. XII. 450 p.). The keynote of the book serves the conviction that Marxism is a sort of “super-theory” that can explain not only any social and political life, but also profound philosophy of science, including natural science. Science is presented in the book as a form of social practice. The main idea of the Marxist philosophy (...) of science is the status of the theory of dialectical materialism. The author shows that Marxist ideas could be considered as the origins of many disciplines: the sociology of science, the history of science, the history of technology; they had a noticeable effect on non-Marxist thought as well. However, Stalinism and Lysenkoism significantly decelerated the development of the Marxist philosophy of science. (shrink)

We comment on the proposition “that lower temperatures and especially greater seasonal variation in temperature call for individuals and societies to adopt … a greater degree of self-control” (Van Lange et al., sect. 3, para. 4) for which we cannot find empirical support in a large data set with data-driven analyses. After providing greater nuance in our theoretical review, we suggest that Van Lange et al. revisit their model with an eye toward the social determinants of self-control.

V nastoi︠a︡shchem izdanii raskryvaetsi︠a︡ biografii︠a︡, a takzhe publikuetsi︠a︡ znachitelʹnai︠a︡ chastʹ ėpistoli︠a︡rnogo nasledii︠a︡ poluzabytogo filosofa Adolʹfa Markovicha Lazareva (1872-1944), odnogo iz blizhaĭshikh druzeĭ, edinomyshlennika i uchenika Lʹva Shestova, istolkovateli︠a︡ ego filosofskikh ideĭ. V knigu vkli︠u︡cheny takzhe statʹi A. Lazareva o L. Shestove -- kak opublikovannye, tak i neizvestnye, sokhranivshiesi︠a︡ v ego arkhive. Prinadlezha k t.n. "shestovskomu" krugu -- k chislu tekh, dli︠a︡ kogo byla blizka i nesomnenna, govori︠a︡ ego sobstvennymi slovami, "volnui︠u︡shchai︠a︡ ubeditelʹnostʹ" mysli velikogo filosofa, A. Lazarev okazalsi︠a︡ fakticheski vne (...) issledovatelʹskogo i chitatelʹskogo vnimanii︠a︡. Dannai︠a︡ kniga i︠a︡vli︠a︡etsi︠a︡, po sushchestvu, pervym opytom privlechʹ interes k ego lichnosti i trudam. (shrink)

In October of 2014, news outlets began reporting on a case of a lesbian couple suing a sperm bank for receiving the wrong donor's sperm.1 As the lawsuit Cramblett v. Midwest Sperm Bank alleged, not only did the couple receive the wrong donor's sperm but they had specifically chosen a white donor with blonde hair and blue eyes and the sperm they received had been from a black donor.2 Both women were white. The couple gave birth to a black/mixed-race child (...) in 2012 and claimed that their daughter's race posed particular challenges for their family, from facing prejudice in their nearly all white community to difficulties dealing with their daughter's hair. The couple sued for "wrongful birth" and "breach of warranty,"... (shrink)

There are some arguments supporting the pessimistic meta-induction, coming from the direction of quantum theory (A. Kukla and J. Walmsley), from the direction of Laudan’s list with successful but false theories, and from the specific direction of the phlogiston theory (whom Kukla Walmsley, and S. Psillos consider to be false). Against these arguments we believe we can successfully oppose, in the first case the interactive quantum realism of I. Niiniluoto, in the second case the realism of the theoretical theoretical constituents (...) responsible for the empirical success of the theories of S. Psillos, and in the third case the analysis of the phlogiston theory done by V. Verronen, R. Vihalemm and E. McMullin (who suggested that this theory was simultaneously insufficiently mature and approximately true). Our conclusion does not necessary prove that the perspective of the scientific realism is true, but rather that the pessimistic meta-induction attack against it proves to be unconvincing. (shrink)